A SSR algorithm, which requires no external training data; SMORE is developed for a common type of MRI acquisition which has high in-plane resolution but low through-plane resolution (thick slices). SMORE enhances edges but does not create structures out of nothing; this reduces the risk of wrongly altering anatomical structures. SMORE gives quantitative improvements on SSIM and PSNR. Applying SMORE as a preprocessing step significantly improves ventricular segmentation accuracy on this brain MRI dataset. SMORE post-processing may allow shorter scan times.